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Agonistes simple et double La diffrence fondamentale entre ces deux molcules est que le semaglutide est un agoniste du GLP-1, cest--dire quil prsente une forte similitude structurale (95%) avec cette hormone et active spcifiquement son rcepteur, tandis que le tirzepatide est un agoniste double, cest--dire quil prsente une structure hybride qui lui permet dactiver la fois les rcepteurs du GLP-1 et du GIP (Figure 2)

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Adults with a BMI of 30 or higher

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Berberine is a plant-derived alkaloid supplement that may influence glucose metabolism through AMPK activation, but is not licensed as a medicine in the UK

Weight regain is possible if you return to previous eating patterns