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Undercover: gene control by metabolites and metabolic enzymes

Skin mast cells carry MRGPRX2, a receptor that fires on cationic, aromatic ("cationic amphiphilic") molecules and releases histamine redness, swelling, the classic wheal. It is confirmed for SS-31, which activates the receptor well below its injection concentration

Such thermo-contractile and self-adjusting hydrogels provide continuous wound coverage and controlled drug release under fluctuating oxidative and mechanical conditions, as demonstrated in recent diabetic wound models

Nijhout HF, Reed MC, Budu P, Ulrich CM

Persons exposed to environmental pollutants and toxins 5

Vitamin B 12 deficiency has been observed in between 40% and 80% of the vegetarian population who do not also take a vitamin B 12 supplement or consume vitamin-fortified food