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It lives in the mucus layer of the intestinal lining, where it feeds on mucin, the glycoprotein that forms the protective barrier between gut bacteria and intestinal cells

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Colonic biopsies from these patients also show reduced GLP-1R expression, suggesting that decreased GLP-1 and GLP-1R expression may underlie the efficacy of ROSE-010 in alleviating IBS-C abdominal pain [61]

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