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doi: 10.1038/s41598-019-52839-6

Derek Lowe, writing on science.org, summarized the conundrum eloquently

Despite its decision to scrap the drug, Pfizer on Monday said those studies met key goals and confirmed a certain form and dose of the pill with the potential to deliver "competitive efficacy and tolerability" in late-stage trials

Oral GLP-1 RAs are also under development, and early data show similar weight loss efficacy to semaglutide 2.4 mg [84], which could improve convenience and potentially reduce costs through improved manufacturing and distribution efficiency

GLP-1(7-36) inhibits atherosclerosis progression in ApoE-/- mouse aorta by lowering expressions of CD36 and ACAT1 in foam cells

Heat the sugar and water in a saucepan over a low heat, stirring, until the sugar dissolves