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In vitro and mouse models of e-cig exposure have found evidence of cell damage and death, increased inflammation, and impaired defenses against both viruses and bacteria (reviewed by (22))

Albrecht A, Felk A, Pichova I, Naglik JR, Schaller M, de Groot P, Maccallum D, Odds FC, Schfer W, Klis F, Monod M, Hube B: Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions

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Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets