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In addition, to facilitate regulatory acceptance, applicants should clearly describe their NAM, including the context in which the NAM will be used (e.g., for screening/prioritization or quantitative risk assessment), the relevance of the model system to human biology and mechanisms of toxicity, and how the NAM informs the toxicological issue/gap

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Over the next four years, tax-paid sales began dropping, though under the new tax rate triple the previous level the state still raised more total revenue than it did under the previous rate

Kilmers experience highlights the importance of recognizing early symptoms and seeking timely care