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ELECTRONIC CIGARETTES: Potential health risks Propylene glycol Primary ingredient in e-cigarettes for producing vapor FDA has classified propylene glycol asgenerally recognized as safe for oral intake Long-term effects associated with pulmonary inhalation are unknown Limited studies suggest adverse effects on airways: Short- and long-term exposure has been associated with respiratory tract irritation1,2 Long-term indoor air exposure might exacerbate and/or induce asthma and rhinitis in children3 1Wieslander et al., Occup Environ Med 2001;58:649-655