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EVIDENCE OF HARM CONTINUES TO EMERGE Data about respiratory effects, secondhand exposure, and long-term smoking cessation efficacy are still limited, and it remains as yet unknown what combinations of solvents, flavorings, and nicotine in a given e-liquid will result in the most harmful or least harmful effects

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But a small proportion of cells went unscathed

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Pathophysiology EDS is caused by defective synthesis or processing of collagen and other connective tissue components due to genetic mutations