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For individuals with pre-existing vascular conditions, smoking can exacerbate problems, leading to complications such as chronic pain or tissue damage

KRAS mutation frequency appeared similar between the two groups

We focused on European ancestry data, although in some cases included multi-ancestry data for mediating factors to optimize power

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Chronic E-Cigarette Aerosol Inhalation Alters the Immune State of the Lungs and Increases ACE2 Expression, Raising Concern for Altered Response and Susceptibility to SARS-CoV-2