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While the Windsor women are known for robust health and longevity, a lifetime of cocktails and cigarettes began to take their toil on Margaret when she reached her 50s

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Alcohol consumption inhibits acinar cell secretion, leading to intra-pancreatic accumulation of digestive enzymes, causing auto-digestion and pancreatic tissue damage

Lewis RS, Bowen SW, Keogh MR, Dewey RE: Three nicotine demethylase genes mediate nornicotine biosynthesis in Nicotiana tabacum L.: Functional characterization of the CYP82E10 gene