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Curr Psychiatry Rep (2014) 16(11):502

The tobacco from the cigarette is mixed with a solvent such as hexane and analysed for its nicotine content

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In fact, while some studies show that, while nicotine might cause cancer, it is possibly one the least cancerogenic ingredients that are added in cigarettes

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Antonello Punturieri, MD, PhD, program director of NHLBIs Chronic Obstructive Pulmonary Disease/Environment Program, said spirometry testing should be used for any patient who shows signs of COPD, airflow obstruction, or who has a history of cigarette smoking