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In the absence of clear evidence on the balance of benefits and harms of pharmacotherapy in pregnant women, clinicians are encouraged to consider the severity of tobacco dependence in each patient and engage in shared decision-making to determine the best individual treatment course

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Following article selection, a template based on the PICOTS [28] (i.e., patient/population, intervention/assessment, comparison, outcome(s), time, study design) was used to extract applicable information from each article